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have made an important discovery: Intermittent calorie restriction leads to significant changes both in the gut and the brain, which may open up new options for maintaining a healthy weight.
Researchers from China studied 25 volunteers classed as obese over a period of 62 days, during which they took part in an intermittent energy restriction program – a regime that involves careful control of calorie intake and relative Not only did the participants in the study lose weight – 7.6 kilograms or 7.8 percent of their body weight on average – there was also evidence of shifts in the activity of obesity-related regions of the brain, and in the make-up ofhealth researcher Qiang Zeng from the Second Medical Center and National Clinical Research Center for Geriatric Diseases in China when the results were published in December 2023.
"The observed changes in the gut microbiome and in the activity in addiction-related brain regions during and after weight loss are highly dynamic and coupled over time." It's not clear what causes these changes, or whether the gut is influencing the brain or vice versa. However, we do know that the gut and the brain arewere negatively associated with activity in the left inferior frontal orbital gyrus, an area involved in executive function, including our willpower when it comes to food intake."The microbiome produces neurotransmitters and neurotoxins which access the brain through nerves and the blood circulation.
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