Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Sciences.
Van Andel Research InstituteAug 1 2024 Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Sciences.
It is the latest discovery from longtime collaborators Huilin Li, Ph.D., of Van Andel Institute, and Michael O'Donnell, Ph.D., of The Rockefeller University, to shed light on the intricate mechanisms that enable the faithful passage of genetic information from generation to generation of cells. To date, at least 40 diseases, including many cancers and rare disorders, have been linked to problems with DNA replication.
On their own, however, polymerases aren't good at staying on the DNA strand. They require CTF18-RFC in humans and Ctf18-RFC in yeast to thread a ring-shaped clamp onto the DNA leading strand, and another clamp loader called RFC in both human and yeast to thread the clamp onto the lagging strand. The clamp then closes and signals to the polymerases that they can begin replicating DNA.
DNA Replication Yeast Cancer Eye Genetic Ph Research
Nigeria Latest News, Nigeria Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Charting an equitable future for DNA and ancient DNA research in AfricaToday, the American Journal of Human Geneticspublished a perspective piece on the need for an equitable and inclusive future for DNA and ancient DNA (aDNA) research in Africa. The paper, coauthored by an international team of 36 scientists from Africa, North America, Asia, Australia, and Europe, was led by Dr.
Read more »
New deadly strain of mpox found in DRC could spread exponentially among humansConcerns are growing about an outbreak of deadly mpox caused by a novel, sexually transmitted strain of the virus in the southeast of the Democratic Republic of Congo (DRC).
Read more »
Powerful visualization technologies offer new insight into understanding muscle contraction in humansThe connections between the nervous system and muscles develop differently across the kingdom of life.
Read more »
New class of cancer mutations discovered in so-called 'junk' DNAUsing artificial intelligence, Garvan Institute researchers have found potential cancer drivers hidden in so-called 'junk' regions of DNA, opening up possibilities for a new approach to diagnosis and treatment.
Read more »
‘Spy in the Bag’ death riddle ‘stinks of cover-up’ says ex-agent who questions key detail of MI6’s ‘appalli...Scotland Yard say they have found no new DNA in latest Body In The Bag update
Read more »
New zwitterionic polyion developed for effective plasmid DNA delivery in muscle cellsResearchers from Tokyo Metropolitan University have created a new drug delivering molecule, a zwitterionic polymer complex that can help get plasmid DNA inside cells when injected into skeletal muscle, a crucial step in the expression of therapeutic RNA and proteins.
Read more »