Researchers have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain -- interconnected systems that support everything from sensory processing to complex decision-making -- paving the way for new insights into brain health and disease.
Rutgers researchers at the Brain Health Institute and Center for Advanced Human Brain Imaging Research have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain -- interconnected systems that support everything from sensory processing to complex decision-making -- paving the way for new insights into brain health and disease., offers a deeper understanding of the cellular foundations of cognition and mental health.
Advances in genetics and technology now allow researchers to study how brain cells are organized in human tissue more precisely. In this study, Rutgers researchers used recently developed post-mortem gene expression atlases, which map how genes are differentially expressed across brain regions, to explore how different types of cells may spatially align with brain networks studies in the general population.
"The study has significant implications for understanding the cellular basis of brain functions across health and disease," Holmes said.
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