Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis

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Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis
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Early therapeutic interventions in inflammatory rheumatic diseases have proven successful in inducing drug-free remission, and EULAR - The European Alliance of Associations for Rheumatology - recommends early intervention in arthritis, since conventional synthetic disease-modifying antirheumatic drugs (csDMARD) have been shown to slow disease...

Jun 13 2024European Alliance of Associations for Rheumatology , EULAR Early therapeutic interventions in inflammatory rheumatic diseases have proven successful in inducing drug-free remission, and EULAR - The European Alliance of Associations for Rheumatology - recommends early intervention in arthritis, since conventional synthetic disease-modifying antirheumatic drugs have been shown to slow disease progression in both rheumatoid and psoriatic arthritis .

At the 2024 EULAR congress, Łukasik and colleagues shared data from their prospective study evaluating the efficacy of a tight control, treat-to-target approach in newly diagnosed, treatment-naïve axSpA patients - following the ASAS-EULAR disease management recommendations. Of 55 patients who completed the trial, 61.8% achieved sustained clinical remission, and 21.8% had low disease activity at Week 52. This the first clinical trial in early axSpA in which sustained inactive disease status has been achieved in over 60% of patients. In univariate analysis, only sex and baseline BASDAI score were significantly different between those who did and did not achieve sustained clinical remission.

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