'This impact has led many researchers around the world to scrutinise in detail the publication in question.'
that led to the World Health Organization suspending clinical trials of the anti-viral drugs as a potential treatment for COVID-19.
The observational research, led by Mandeep Mehra of the Brigham and Women's Hospital in the US, looked at records from 96,000 patients in hundreds of hospitals between December and April and compared those who received treatment with a control group. "This impact has led many researchers around the world to scrutinise in detail the publication in question," said the open letter in response to the study, which was signed by a number of prominent scientists and published Thursday.One of the main concerns was a lack of information about the countries and hospitals that contributed data, which was provided by Chicago-based healthcare data analytics firm Surgisphere.
"The Lancet encourages scientific debate and will publish responses to the study, along with a response from the authors, in the journal in due course," it said, adding that the conclusion of the study remained unchanged.Mehra also released a statement saying the authors of the study had initiated an academic review of their work, adding that it had been undertaken"in the absence of a large, robust and publicly available dataset on hydroxychloroquine or chloroquine".
A spokesman for the WHO said a comprehensive review of the drugs was expected to reach a conclusion in mid-June. "I have serious doubts about the benefit of CQ/HCQ treatment for #COVID19 infection, and cannot wait for the whole drama to be over," he said on Twitter.
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