While many drug trials are still ongoing, a preliminary study shows dexamethasone has potential for treatment of critically ill COVID-19 patients
World Health Organisation Director-General, Tedros Ghebreyesus at the coronavirus press conference in GenevaThe World Health Organisation , last week, welcomed initial clinical trial results from the United Kingdom that showed dexamethasone, a corticosteroid, can help patients who are critically ill withScientists are in a race to find a cure or vaccine for the disease.
Dexamethasone is a corticosteroid used in a wide range of conditions for its anti-inflammatory and immunosuppressant effects. In pregnancy or breastfeeding women, patients were randomized to prednisolone 40 mg administered by mouth.: WHO is in the process of updating treatment guidelines to include dexamethasone or other steroids.: Yes, dexamethasone has been on the WHO Model List of Essential Medicines since 1977 for several indications in multiple formulations. Since 2013, dexamethasone has been indicated for respiratory distress syndrome in new-borns. Prednisolone is also on the EML and was included in 1984.
Note: It is permitted to switch between the two routes of administration according to clinical circumstances.Question: What are the typical side effects of dexamethasone?: Dexamethasone is generally safe. It presents a favourable benefit-risk profile, particularly in patients with severe forms of pneumonia, while the benefit is less prominent in patients with non-severe pneumonia. As the treatment is short, even at high doses, corticosteroids are not associated with serious side effects.
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