New Oxford study shows progress in potential COVID-19 vaccine

The vaccine has been evaluated in more than 1,000 healthy adult volunteers aged between 18 and 55 years in a randomised controlled trials.

Oxford and AstraZeneca are collaborating with clinical partners around the world as part of a global clinical programme to get a vaccine.

The vaccine provoked a T cell response within 14 days of vaccination , and an antibody response within 28 days .During the study, participants who received the vaccine had detectable neutralising antibodies, which have been suggested by researchers as important for protection, and these responses were strongest after a booster dose, with 100 per cent of participants’ blood having neutralising activity against the coronavirus.

A UK Phase I/II trial began in April testing the Oxford coronavirus vaccine ChAdOx1 nCoV-19. The team started working to develop a vaccine against the global threat in January 2020 and have been working with unprecedented urgency in a race against the coronavirus. The University of Oxford is working with the UK-based global biopharmaceutical company AstraZeneca for the further development, large-scale manufacture and potential distribution of the vaccine, with plans for clinical development and production of the Oxford vaccine progressing globally.

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